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Form	MW
CRBN ligand-870 This page	356.38
RR-11055	356.38

CRBN ligand-870

Ligand for E3 Ligase

CRBN ligand-870 is a ligand for the E3 ubiquitin ligase cereblon (CRBN) that facilitates the recruitment of the CRBN protein. This compound can be utilized in the design of PROTACs (proteolysis-targeting chimeras) by linking it to target protein ligands via a suitable linker. CRBN ligand-870 is instrumental in studying the targeted degradation of specific proteins, contributing to advancements in therapeutic strategies and research in cellular regulation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	3026010-13-6
Applications	Ligand for E3 Ligase
Formula	C₁₈H₂₀N₄O₄
Molecular Weight	356.38
SMILES	O=C1C=2C(=C3C(N4[C@](CO3)(CNCC4)[H])=CC2)CN1[C@@H]5C(=O)NC(=O)CC5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.