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Form	MW
RR-11055 This page	356.38
CRBN ligand-870	356.38

RR-11055

E3 Ligase Ligand

RR-11055 is a ligand for the E3 ligase cereblon, demonstrating a binding affinity with a Ki value of 0.38 μM. This compound is instrumental in the synthesis of PROTAC degrader ERD-1233, making it valuable for research in targeted protein degradation and modular drug design. Its ability to interact with E3 ligases positions RR-11055 as a significant tool for studying ubiquitin-mediated proteolysis.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	3026009-09-3
Applications	E3 Ligase Ligand
Formula	C₁₈H₂₀N₄O₄
Molecular Weight	356.38
SMILES	O=C1C2=CC=C(N3[C@@](CNCC3)([H])CO4)C4=C2CN1[C@@H]5C(NC(CC5)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.