Fig. 1 · Structure

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CRTh2 antagonist 2

CRTh2 Antagonist

CRTh2 Antagonist 2 is a selective and potent CRTh2 receptor antagonist, exhibiting an IC50 of ≤10 nM. This compound is primarily utilized in research related to androgenic alopecia, offering valuable insights into the modulation of hair growth and related pathways. Its high specificity makes it an essential tool for investigating the therapeutic potential in hair loss disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 780763-95-3
Applications CRTh2 Antagonist
Formula C26H23ClN4O3
Molecular Weight 474.94
SMILES
O=C(O)CC1=C(N(C)C)N=C(CC2=CC=C(NC(C3=CC=C4C=CC=CC4=C3)=O)C=C2)N=C1Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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