CRTH2-IN-1

Catalog No.: A63427
Prostaglandin Receptor Antagonist
CRTH2-IN-1 is a selective antagonist of the prostaglandin D2 receptor, also known as CRTH2, with an IC50 value of 6 nM in human DP2 binding assays. This compound is utilized in research focused on elucidating the role of DP2 in various biological pathways, including inflammation and immune response. Its properties make it a valuable tool for investigating therapeutic strategies in conditions associated with prostaglandin signaling.
Grouped product items
Size Price Stock Qty
25mg
$1,530.00
In stock
50mg
$1,950.00
In stock
100mg
$2,480.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCRTH2-IN-1 is a selective antagonist of the prostaglandin D2 receptor, also known as CRTH2, with an IC50 value of 6 nM in human DP2 binding assays. This compound is utilized in research focused on elucidating the role of DP2 in various biological pathways, including inflammation and immune response. Its properties make it a valuable tool for investigating therapeutic strategies in conditions associated with prostaglandin signaling.
Product Information
Catalog NumA63427
FormulaC21H21FN2O4S
Molecular Weight416.47
CAS Number926661-54-3
SMILESO=C(O)CC1=C(CCC(N(S(=O)(C2=CC=C(F)C=C2)=O)C)C3)N3C4=C1C=CC=C4
SynonymsRamatroban analog
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