Fig. 1 · Structure
Documents & Downloads
CS1
DNA Topo II α Inhibitor
CS1 is a potent inhibitor of DNA Topoisomerase II α, a crucial enzyme involved in DNA replication and cell division. This compound exhibits broad-spectrum antitumor activity in vitro, demonstrating low toxicity in vivo and the potential to counteract multidrug resistance. CS1 induces DNA damage, leads to cell cycle arrest at the G2/M phase, and promotes apoptosis, making it a valuable tool for cancer research applications.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1448009-94-6 |
| Applications | DNA Topo II α Inhibitor |
| Formula | C16H12O3 |
| Molecular Weight | 252.26 |
| SMILES | OC1=CC=C(C2=CC=C3C=C(O)C=CC3=C2)C=C1O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.