CSP-2503 is a highly selective agonist of the 5-HT1A receptor, exhibiting an EC50 of 0.15 μM and a Ki value of 4.1 nM. This compound demonstrates significant selectivity against α1-adrenoceptors, 5-HT4 receptors, and benzodiazepine receptors, with Ki values exceeding 1000 nM. CSP-2503 reduces cAMP levels in vitro and displays anxiolytic effects in vivo, making it a valuable tool for investigating anxiety-related disorders.
CSP-2503 is a highly selective agonist of the 5-HT1A receptor, exhibiting an EC50 of 0.15 μM and a Ki value of 4.1 nM. This compound demonstrates significant selectivity against α1-adrenoceptors, 5-HT4 receptors, and benzodiazepine receptors, with Ki values exceeding 1000 nM. CSP-2503 reduces cAMP levels in vitro and displays anxiolytic effects in vivo, making it a valuable tool for investigating anxiety-related disorders.
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