Fig. 1 · Structure

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CTTHWGFTLC, CYCLIC

MMP-2/9 Inhibitor

CTTHWGFTLC, CYCLIC is a cyclic peptide that selectively inhibits matrix metalloproteinases MMP-2 and MMP-9. This compound demonstrates an IC50 value of approximately 8 μM for MMP-9, making it a valuable tool for studying the roles of these enzymes in various biological processes. It is particularly applicable in research focused on cancer metastasis, tissue remodeling, and inflammatory responses.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 244082-19-7
Applications MMP-2/9 Inhibitor
Formula C52H71N13O14S2
Molecular Weight 1166.33
SMILES
C(C=1C=2C(NC1)=CC=CC2)[C@@H]3NC(=O)[C@H](CC4=CN=CN4)NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@@H](N)CSSC[C@@H](C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@H](CC5=CC=CC=C5)NC(=O)CNC3=O)[H])[H])[H]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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