Fig. 1 · Structure
Documents & Downloads
Cudetaxestat
ATX Inhibitor
Cudetaxestat is a potent noncompetitive inhibitor of autotaxin (ATX), targeting the enzyme responsible for the production of lysophosphatidic acid (LPA). By inhibiting ATX activity, Cudetaxestat diminishes LPA synthesis and interferes with the ATX-LPA signaling pathway. This compound retains nanomolar-level efficacy even in the presence of elevated lysophosphatidylcholine (LPC) concentrations. Cudetaxestat is applicable in preclinical research related to conditions such as fibrosis, tumor metastasis, inflammation, and other autoimmune disorders.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1782070-21-6 |
| Applications | ATX Inhibitor |
| Formula | C21H15Cl2F2N3O2S |
| Molecular Weight | 482.33 |
| Synonyms | BLD-0409; PAT-409 |
| SMILES | O=C(C1=C(F)C(SC2=C(N(C3=C2C=CC(Cl)=C3F)C4=CN(CCC)N=C4)Cl)=CC=C1)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.