Fig. 1 · Structure
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Cuprizone
Copper Chelator
Cuprizone is a copper chelator that forms a distinct blue complex with copper (II), making it useful for colorimetric detection of trace copper levels. It is employed in animal models to induce schizophrenia-like behaviors, enabling the study of psychiatric conditions. Cuprizone primarily affects copper-dependent enzymes, such as superoxide dismutase 1 (SOD1) and cytochrome oxidase, leading to oxidative stress and increased dopamine levels in brain regions like the medial prefrontal cortex (PFC). This reagent is valuable for research involving neurobiology and oxidative stress mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 370-81-0 |
| Applications | Copper Chelator |
| Formula | C14H22N4O2 |
| Molecular Weight | 278.35 |
| SMILES | O=C(C(N/N=C1CCCCC\1)=O)N/N=C2CCCCC/2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.