CX-4945 sodium salt

Catalog No.: A16234

CK2 inhibitor

CX-4945 sodium salt

CX-4945 sodium salt Chemical Structure

CAS NO. 1309357-15-0

CX-4945 sodium salt is a potent and selective ATP-competitive small molecule protein kinase CK2 inhibitor with a Ki and an IC50 of 0.38 and 1 nM for recombinant human CK2α, respectively.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $60.00

Special Price $48.00

10 mg

Regular Price: $100.00

Special Price $80.00

50 mg

Regular Price: $320.00

Special Price $256.00

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Biological Activity

CX-4945 sodium salt is a potent and selective ATP-competitive small molecule protein kinase CK2 inhibitor with a Ki and an IC50 of 0.38 and 1 nM for recombinant human CK2α, respectively.
In vitro DMSO 65 mg/mL (174.84 mM)
Water 65 mg/mL (174.84 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.9 mL 134.5 mL 269 mL
0.5 mM 5.38 mL 26.9 mL 53.8 mL
1 mM 2.69 mL 13.45 mL 26.9 mL
5 mM 0.54 mL 2.69 mL 5.38 mL

*The above data is based on the productmolecular weight 371.75. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16234
Actions Inhibitor
CAS No. 1309357-15-0
Formula C19H11ClN3NaO2
M. Wt 371.75
Purity >98%
Synonyms Silmitasertib sodium salt
SMILES [O-]C(C1=CC=C2C(N=C(NC3CC(Cl)CCC3)C4=C2C=NC=C4)=C1)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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