Cyclazosin hydrochloride

Catalog No.: A58415
Adrenaline Receptor Antagonists
Cyclazosin hydrochloride is an α1B-adrenergic receptor antagonist that exhibits high specificity for α-adrenergic receptors, with reported pKi values ranging from 9.23 to 9.57 for O/1A and 8.18 to 8.41 for OflB receptors. This compound is utilized in research to study the role of α-adrenergic signaling in various physiological processes and to explore potential therapeutic applications in conditions influenced by adrenergic activity. However, Cyclazosin hydrochloride does not differentiate between cloned alb and alo adrenergic receptor subtypes, exhibiting similar affinity profiles.
Grouped product items
Size Price Stock Qty
1mg
$140.00
In stock
5mg
$355.00
In stock
10mg
$495.00
In stock
25mg
$765.00
In stock
50mg
$970.00
In stock
100mg
$1,265.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCyclazosin hydrochloride is an α1B-adrenergic receptor antagonist that exhibits high specificity for α-adrenergic receptors, with reported pKi values ranging from 9.23 to 9.57 for O/1A and 8.18 to 8.41 for OflB receptors. This compound is utilized in research to study the role of α-adrenergic signaling in various physiological processes and to explore potential therapeutic applications in conditions influenced by adrenergic activity. However, Cyclazosin hydrochloride does not differentiate between cloned alb and alo adrenergic receptor subtypes, exhibiting similar affinity profiles.
Product Information
Catalog NumA58415
FormulaC23H28ClN5O4
Molecular Weight473.95
CAS Number146929-33-1
SMILESCOC1=CC2=NC(N3CCN(C(C4=CC=CO4)=O)[C@@]5([H])CCCC[C@@]35[H])=NC(N)=C2C=C1OC.Cl
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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