Cyclic somatostatin acetate

Catalog No.: A73393
Peptide
Cyclic somatostatin acetate is a neuropeptide that primarily targets growth hormone release inhibition. It plays a critical role in cardiovascular research by modulating the contractile response of ventricular cardiomyocytes, with an IC50 value of 13 nM against isoprenaline. This reagent is utilized in studies investigating severe acute hemorrhages associated with gastroduodenal ulcers and provides insights into the mechanisms underlying cardiovascular diseases.
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Size Price Stock Qty
1mg
$40.00
In stock
10mg
$60.00
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25mg
$100.00
In stock
50mg
$145.00
In stock
100mg
$230.00
In stock
200mg
$390.00
In stock
500mg
$635.00
In stock
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCyclic somatostatin acetate is a neuropeptide that primarily targets growth hormone release inhibition. It plays a critical role in cardiovascular research by modulating the contractile response of ventricular cardiomyocytes, with an IC50 value of 13 nM against isoprenaline. This reagent is utilized in studies investigating severe acute hemorrhages associated with gastroduodenal ulcers and provides insights into the mechanisms underlying cardiovascular diseases.
Product Information
Catalog NumA73393
FormulaC78H108N18O21S2
Molecular Weight1697.93
CAS Number54472-66-1
SequenceAla-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys (Disulfide bridge: Cys3-Cys14)
Sequence shorteningAGCKNFFWKTFTSC-OH (Disulfide bridge: Cys3-Cys14)
SMILESCC(O)=O.C[C@@H](O)[C@@H]1NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC1=O)[C@@H](C)O)C(O)=O)NC(=O)CNC(=O)[C@H](C)N
SynonymsSRIF-14 acetate; Somatostatin-14 acetate
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