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Cyclic tri-AMP

DNA Endonuclease Activator

Cyclic tri-AMP is a DNA endonuclease activator that functions as a crucial second messenger in the cyclic oligonucleotide-based anti-phage signaling system (CBASS). It mediates the immune response against viral infections by binding to and activating the DNA endonuclease NucC, leading to cellular apoptosis and exhibiting significant antiviral activity. This compound is valuable for research applications focused on virology and mechanisms of host defense.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Activator
CAS Number	54447-85-7
Applications	DNA Endonuclease Activator
Formula	C₃₀H₃₆N₁₅O₁₈P₃
Molecular Weight	987.62
SMILES	O[C@H]1[C@](O[C@@](CO[P](O)(O[C@]2([H])[C@](CO3)([H])O[C@](N4C5=NC=NC(N)=C5N=C4)([H])[C@@H]2O)=O)([H])[C@@]1([H])O[P](O)(OC[C@](O[C@@]6([H])N7C8=NC=NC(N)=C8N=C7)([H])[C@](O[P]3(O)=O)([H])[C@H]6O)=O)([H])N9C%10=NC=NC(N)=C%10N=C9

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.