Cyclooctyne-O-NHS ester is a versatile ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs). This compound features an alkyne group, allowing for efficient click chemistry applications, specifically through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its reactivity and cleavable nature make it an essential tool for developing targeted therapies in chemical biology and drug development.
Cyclooctyne-O-NHS ester is a versatile ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs). This compound features an alkyne group, allowing for efficient click chemistry applications, specifically through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its reactivity and cleavable nature make it an essential tool for developing targeted therapies in chemical biology and drug development.
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