Fig. 1 · Structure
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Cyclopropylboronic acid
Intermediate
Cyclopropylboronic acid serves as a versatile intermediate in organic synthesis. It is particularly valuable for the development of EGFR kinase inhibitors, such as Compound 25, which exhibits antiproliferative effects on EGFR mutant cells, including those with the Δ19del/T790M/C797S mutations. This compound is relevant for applications in lung cancer research, providing insights into targeted therapies for this malignancy.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 411235-57-9 |
| Applications | Intermediate |
| Formula | C3H7BO2 |
| Molecular Weight | 85.90 |
| SMILES | OB(C1CC1)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.