Cyclosporin A-Derivative 1 Free base

Name: Cyclosporin A-Derivative 1 Free base
Brand: Adooq Bioscience
SKU: A64596
Rating: 5 (288 reviews)

Catalog No.: A64596

Calcineurin Inhibitor

Cyclosporin A-Derivative 1 (Free base) acts as a potent calcineurin inhibitor through its interaction with cyclophilin. This compound is derived from cyclosporin A and plays a critical role in immunosuppression by inhibiting T-lymphocyte activation. It is primarily utilized in research applications focused on transplant immunology and autoimmune disease modeling.

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Cyclosporin A-Derivative 1 Free base 286852-20-8 Calcineurin Inhibitor

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Grouped product items
Size	Price	Stock
1mg	$235.00	In stock
5mg	$285.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	Cyclosporin A-Derivative 1 (Free base) acts as a potent calcineurin inhibitor through its interaction with cyclophilin. This compound is derived from cyclosporin A and plays a critical role in immunosuppression by inhibiting T-lymphocyte activation. It is primarily utilized in research applications focused on transplant immunology and autoimmune disease modeling.

Product Information

Catalog Num	A64596
Formula	C65H117N11O14
Molecular Weight	1276.69
CAS Number	286852-20-8
Sequence	Leu-Val-Leu-Ala-{d-Ala}-Leu-Leu-Val-{Aaa}-{Abu}-{Sar}
Sequence shortening	LVLA-{d-Ala}-LLV-{Aaa}-{Abu}-{Sar}
SMILES	[H][C@](NC(=O)[C@H](CC(C)C)NC)(C(C)C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@H](C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N(C)[C@@]([H])(C(C)C)C(=O)N(C)[C@@]([H])([C@H](OC(C)=O)[C@H](C)C\C=C\C)C(=O)N[C@@H](CC)C(=O)N(C)CC(=O)OC

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