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Cyclosporin A-Derivative 3

Calcineurin Inhibitor

Cyclosporin A-Derivative 3 is a potent calcineurin inhibitor that effectively modulates T-cell activation and immune response. This compound is valuable in research applications focused on immunology, transplantation, and autoimmune diseases, offering insights into the mechanisms of immune regulation. Its derivatives provide a distinct approach for studying calcineurin’s role in cellular signaling pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	121584-34-7
Applications	Calcineurin Inhibitor
Formula	C₆₃H₁₁₁N₁₁O₁₂
Molecular Weight	1214.62
SMILES	[C@H]([C@@H](C/C=C\C=C)C)(O)[C@@]1(N(C)C(=O)[C@H]([C@H](C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H]([C@H](C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)[C@H](CC)NC1=O)[H]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.