Fig. 1 · Structure

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Cyclothialidine D

DNA Helicase Inhibitor

Cyclothialidine D is a selective inhibitor of Escherichia coli DNA helicases, with an IC50 of 0.7 μM. This compound serves as a valuable tool in molecular biology research, enabling the study of DNA replication and repair mechanisms. Its ability to inhibit helicase activity provides insights into cellular processes and potential therapeutic targets in bacterial systems.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 194276-78-3
Applications DNA Helicase Inhibitor
Formula C24H31N5O11S
Molecular Weight 597.59
SMILES
O=C(N[C@@H](CSCC1=C(O)C=C(O)C=C1C(OC2)=O)C(NCC(O)=O)=O)[C@H]2NC([C@H]3N(CC[C@H]3O)C([C@@H](N)C)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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