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sphingosine-1-phosphate receptor 4 (S1P4-R) agonist
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| Cell Line | Activity | Value | Description | Reference |
|---|---|---|---|---|
| U2OS | EC50 | 56 nM | Agonist activity at S1P4 receptor in human U2OS cells expressing VP16-GAL4 transcriptional factor and beta-arrestin/TEV protease fusion protein assessed as migration of VP16-GAL4 into nucleus by FRET based beta lactamase reporter gene assay | [PMID: 21982495] |
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 1345858-76-5 |
| Applications | sphingosine-1-phosphate receptor 4 (S1P4-R) agonist |
| Formula | C20H21F2N3O2S |
| Molecular Weight | 405.46 |
| Synonyms | ML248 |
| SMILES | O=C1N(C)/C(S/C1=C\C2=C(C)N(C3=CC=C(F)C=C3F)C(C)=C2)=N/CCOC |
No reported solubility data are available for this product.
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
