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(Cys(Bzl)84,Glu(OBzl)85)CD4 (81-92)

Catalog No.: A51605
HIV Inhibitor
[(Cys(Bzl)84,Glu(OBzl)85)]CD4 (81-92) functions as a selective inhibitor of HIV-1 by obstructing the interaction between the virus and CD4 molecules. This compound demonstrates significant antiviral activity by effectively inhibiting viral infection and cell fusion. Research applications include studies focused on HIV treatment mechanisms and exploration of CD4 receptor interactions, with complete inhibition of fusion formation observed at a concentration of 25 μM.
[(Cys(Bzl)84,Glu(OBzl)85)]CD4 (81-92) 124699-95-2 HIV Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description[(Cys(Bzl)84,Glu(OBzl)85)]CD4 (81-92) functions as a selective inhibitor of HIV-1 by obstructing the interaction between the virus and CD4 molecules. This compound demonstrates significant antiviral activity by effectively inhibiting viral infection and cell fusion. Research applications include studies focused on HIV treatment mechanisms and exploration of CD4 receptor interactions, with complete inhibition of fusion formation observed at a concentration of 25 μM.
Product Information
Catalog NumA51605
FormulaC76H108N14O26S
Molecular Weight1665.81
CAS Number124699-95-2
SequenceThr-Tyr-Ile-{Cys(Bzl)}-{Glu(OBzl)}-Val-Glu-Asp-Gln-Lys-Glu-Glu
Sequence shorteningTYI-{Cys(Bzl)}-{Glu(OBzl)}-VEDQKEE
SMILES[C@H](CC1=CC=C(O)C=C1)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCC(O)=O)C(O)=O)=O)CCC(O)=O)=O)CCCCN)=O)CCC(N)=O)=O)CC(O)=O)=O)CCC(O)=O)=O)[C@H](C)C)=O)CCC(OCC2=CC=CC=C2)=O)=O)CSCC3=CC=CC=C3)=O)[C@H](CC)C)=O)NC([C@H]([C@@H](C)O)N)=O
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Microbiology > Antifection > HIV