CZh226

Catalog No.: A54791
PAK4 Inhibitor
CZh226 is a selective inhibitor of PAK4 with an IC50 of 0.0111 μM and a Ki of 0.009 μM. This compound effectively inhibits PAK4 activity, leading to decreased phosphorylation of its downstream signaling molecules. CZh226 has demonstrated the ability to inhibit the migration and invasion of tumor cells, making it a valuable reagent for research related to lung cancer and other PAK4-mediated pathways.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCZh226 is a selective inhibitor of PAK4 with an IC50 of 0.0111 μM and a Ki of 0.009 μM. This compound effectively inhibits PAK4 activity, leading to decreased phosphorylation of its downstream signaling molecules. CZh226 has demonstrated the ability to inhibit the migration and invasion of tumor cells, making it a valuable reagent for research related to lung cancer and other PAK4-mediated pathways.
Product Information
Catalog NumA54791
FormulaC20H22ClN7O
Molecular Weight411.89
CAS Number2196199-00-3
SMILESN(C=1C2=C(N=C(C(=O)N3C[C@@H](C)NCC3)N1)C=CC(Cl)=C2)C=4C=C(NN4)C5CC5
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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