(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P

Name: (D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P
Brand: Adooq Bioscience
SKU: A62123
Rating: 5 (288 reviews)

Catalog No.: A62123

Substance P Antagonist

(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P is a potent antagonist of the neuropeptide Substance P. This compound specifically inhibits the neurokinin-1 receptor (NK1R), playing a significant role in modulating pain perception and inflammatory responses. It is commonly utilized in research focused on pain management, neurobiology, and the exploration of neuropeptide signaling pathways.

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(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P 84676-91-5 Substance P Antagonist

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Biological Activity

Description	(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P is a potent antagonist of the neuropeptide Substance P. This compound specifically inhibits the neurokinin-1 receptor (NK1R), playing a significant role in modulating pain perception and inflammatory responses. It is commonly utilized in research focused on pain management, neurobiology, and the exploration of neuropeptide signaling pathways.

Product Information

Catalog Num	A62123
Formula	C75H108N20O13
Molecular Weight	1497.79
CAS Number	84676-91-5
Sequence	{D-Arg}-{D-Pro}-Lys-Pro-Gln-Gln-{D-Trp}-Phe-{D-Trp}-Leu-Leu-NH?
Sequence shortening	{D-Arg}-{D-Pro}-KPQQ-{D-Trp}-F-{D-Trp}-LL-NH2
SMILES	C([C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](CC=2C=3C(NC2)=CC=CC3)C(N[C@H](C(N[C@@H](CC(C)C)C(N)=O)=O)CC(C)C)=O)=O)=O)NC([C@@H](NC([C@@H](NC(=O)[C@H]4N(C([C@@H](NC(=O)[C@@H]5N(C([C@@H](CCCNC(=N)N)N)=O)CCC5)CCCCN)=O)CCC4)CCC(N)=O)=O)CCC(N)=O)=O)C=6C=7C(NC6)=CC=CC7

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