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(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P

Substance P Antagonist

(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P is a potent antagonist of the neuropeptide Substance P. This compound specifically inhibits the neurokinin-1 receptor (NK1R), playing a significant role in modulating pain perception and inflammatory responses. It is commonly utilized in research focused on pain management, neurobiology, and the exploration of neuropeptide signaling pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	84676-91-5
Applications	Substance P Antagonist
Formula	C₇₅H₁₀₈N₂₀O₁₃
Molecular Weight	1497.79
SMILES	C([C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](CC=2C=3C(NC2)=CC=CC3)C(N[C@H](C(N[C@@H](CC(C)C)C(N)=O)=O)CC(C)C)=O)=O)=O)NC([C@@H](NC([C@@H](NC(=O)[C@H]4N(C([C@@H](NC(=O)[C@@H]5N(C([C@@H](CCCNC(=N)N)N)=O)CCC5)CCCCN)=O)CCC4)CCC(N)=O)=O)CCC(N)=O)=O)C=6C=7C(NC6)=CC=CC7

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.