D-Erythro-dihydrosphingosine

Catalog No.: A71168
Endogenous Metabolite
D-Erythro-dihydrosphingosine is a potent inhibitor of cytosolic phospholipase A2α (cPLA2α), a key enzyme involved in phospholipid metabolism and inflammatory processes. Its inhibition of cPLA2α activity makes it a valuable tool for research into lipid signaling pathways and inflammatory diseases. This endogenous metabolite can be utilized in studies aimed at understanding the regulatory mechanisms of cell membrane dynamics and associated pathophysiological conditions.
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2mg
$25.00
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5mg
$40.00
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10mg
$70.00
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25mg
$125.00
In stock
50mg
$295.00
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionD-Erythro-dihydrosphingosine is a potent inhibitor of cytosolic phospholipase A2α (cPLA2α), a key enzyme involved in phospholipid metabolism and inflammatory processes. Its inhibition of cPLA2α activity makes it a valuable tool for research into lipid signaling pathways and inflammatory diseases. This endogenous metabolite can be utilized in studies aimed at understanding the regulatory mechanisms of cell membrane dynamics and associated pathophysiological conditions.
Product Information
Catalog NumA71168
FormulaC18H39NO2
Molecular Weight301.51
CAS Number764-22-7
SMILESCCCCCCCCCCCCCCC[C@@H](O)[C@@H](N)CO
SynonymsSphinganine (d18:0)
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