Fig. 1 · Structure
Documents & Downloads
D-Ile-Pro-Arg p-nitroanilide dihydrochloride
tPA Substrate
D-Ile-Pro-Arg p-nitroanilide dihydrochloride serves as a chromogenic peptide substrate for tissue plasminogen activator (tPA). This compound enables the study of tPA activity through the quantification of its enzymatic cleavage, facilitating investigations into fibrinolytic processes. It is commonly utilized in research applications focused on thrombolysis and related cardiovascular studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Substrate |
| CAS Number | 96323-41-0 |
| Applications | tPA Substrate |
| Formula | C23H38Cl2N8O5 |
| Molecular Weight | 577.50 |
| SMILES | [O-][N+](C(C=C1)=CC=C1NC([C@H](CCCNC(N)=N)NC([C@H]2N(CCC2)C([C@H](N)[C@H](C)CC)=O)=O)=O)=O.Cl.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.