Fig. 1 · Structure

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D-Luciferin 6′-methyl ether (6′-Methoxyluciferin)

PpyLuc Inhibitor

D-Luciferin 6'-methyl ether is a potent inhibitor of the Photinus pyralis luciferase (PpyLuc), with an IC50 value of 0.1 µM. This D-luciferin analog exhibits non-specific interactions at the ATP and luciferin-binding sites within the active site of PpyLuc. It is utilized in various research applications, particularly in studying bioluminescence and enzyme kinetics related to luciferase activity.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 24404-90-8
Applications PpyLuc Inhibitor
Formula C12H10N2O3S2
Molecular Weight 294.35
Synonyms 6′-Methoxyluciferin
SMILES
OC([C@@H]1N=C(SC1)C(SC2=C3)=NC2=CC=C3OC)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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