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D-Pro2,D-Phe7,D-Trp9 Substance P

Substance P Inhibitor

[D-Pro2,D-Phe7,D-Trp9] Substance P is a synthetic analogue of Substance P that functions as a potent inhibitor of the neuropeptide. It exhibits a significant ability to modulate neurogenic inflammation and pain response by blocking Substance P-mediated signaling pathways. This compound is useful in studying the role of Substance P in pain and gastrointestinal motility research applications, particularly in models involving guinea-pig ileum contraction.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	77275-70-8
Applications	Substance P Inhibitor
Formula	C₇₂H₁₀₅N₁₉O₁₃S
Molecular Weight	1476.79
SMILES	C([C@@H](NC([C@@H](NC([C@@H](CC1=CC=CC=C1)NC([C@@H](NC([C@@H](NC(=O)[C@H]2N(C([C@@H](NC(=O)[C@@H]3N(C([C@H](CCCNC(=N)N)N)=O)CCC3)CCCCN)=O)CCC2)CCC(N)=O)=O)CCC(N)=O)=O)=O)CC4=CC=CC=C4)=O)C(N[C@H](C(N[C@@H](CCSC)C(N)=O)=O)CC(C)C)=O)C=5C=6C(NC5)=CC=CC6

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.