D13-9001

Catalog No.: A18570

AcrB and MexB inhibitor

D13-9001

D13-9001 Chemical Structure

CAS NO. 957471-96-4

D13-9001 is a potent AcrB (AcrAB-TolC efflux pump subunit) and MexB (MexAB-OprM efflux pump subunit) inhibitor with the KD values of 1.15 μM and 3.57 μM in E. coli and P. aeruginosa, respectively. D13-9001 exhibits antibiotic activities.

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$650.00
50 mg
$2,000.00
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Biological Activity

D13-9001 is a potent AcrB (AcrAB-TolC efflux pump subunit) and MexB (MexAB-OprM efflux pump subunit) inhibitor with the KD values of 1.15 μM and 3.57 μM in E. coli and P. aeruginosa, respectively. D13-9001 exhibits antibiotic activities.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.41 mL 72.07 mL 144.14 mL
0.5 mM 2.88 mL 14.41 mL 28.83 mL
1 mM 1.44 mL 7.21 mL 14.41 mL
5 mM 0.29 mL 1.44 mL 2.88 mL

*The above data is based on the productmolecular weight 693.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18570
Actions Inhibitor
CAS No. 957471-96-4
Formula C31H39N11O6S
M. Wt 693.78
Purity >98%
Synonyms D139001
SMILES O=C(NCC[N+](C)(CC([O-])=O)C)O[[email protected]]1CN(C(N=C2N3C=CC(C(NC4=NC(C(C)(C)C)=CS4)=O)=C2)=C(/C=C/C5=NN=NN5)C3=O)CCC1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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