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Biological Activity
D13-9001 is a potent AcrB (AcrAB-TolC efflux pump subunit) and MexB (MexAB-OprM efflux pump subunit) inhibitor with the KD values of 1.15 μM and 3.57 μM in E. coli and P. aeruginosa, respectively. D13-9001 exhibits antibiotic activities.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 14.41 mL | 72.07 mL | 144.14 mL |
| 0.5 mM | 2.88 mL | 14.41 mL | 28.83 mL |
| 1 mM | 1.44 mL | 7.21 mL | 14.41 mL |
| 5 mM | 0.29 mL | 1.44 mL | 2.88 mL |
*The above data is based on the productmolecular weight 693.78. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18570 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 957471-96-4 |
| Formula | C31H39N11O6S |
| M. Wt | 693.78 |
| Purity | >98% |
| Synonyms | D139001 |
| SMILES | O=C(NCC[N+](C)(CC([O-])=O)C)O[C@H]1CN(C(N=C2N3C=CC(C(NC4=NC(C(C)(C)C)=CS4)=O)=C2)=C(/C=C/C5=NN=NN5)C3=O)CCC1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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Contact information
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