Dabigatran-d4 is a deuterated form of Dabigatran, a potent and reversible direct thrombin inhibitor with a Ki of 4.5 nM. This oral anticoagulant is effective in preventing thrombin-induced platelet aggregation, exhibiting an IC50 value of 10 nM. Dabigatran-d4 can be utilized in pharmacokinetic studies and metabolic research, providing a valuable tool for understanding thrombin inhibition in various biological contexts.
Dabigatran-d4 is a deuterated form of Dabigatran, a potent and reversible direct thrombin inhibitor with a Ki of 4.5 nM. This oral anticoagulant is effective in preventing thrombin-induced platelet aggregation, exhibiting an IC50 value of 10 nM. Dabigatran-d4 can be utilized in pharmacokinetic studies and metabolic research, providing a valuable tool for understanding thrombin inhibition in various biological contexts.
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