Dabigatran-d7 is a deuterium-labeled analog of Dabigatran, a potent, reversible direct thrombin inhibitor with a Ki of 4.5 nM. This compound effectively inhibits thrombin-induced platelet aggregation, demonstrating an IC50 of 10 nM. Dabigatran-d7 is utilized in pharmacokinetic studies and tracer applications to investigate metabolism and drug interactions in anticoagulation research.
Dabigatran-d7 is a deuterium-labeled analog of Dabigatran, a potent, reversible direct thrombin inhibitor with a Ki of 4.5 nM. This compound effectively inhibits thrombin-induced platelet aggregation, demonstrating an IC50 of 10 nM. Dabigatran-d7 is utilized in pharmacokinetic studies and tracer applications to investigate metabolism and drug interactions in anticoagulation research.
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