Fig. 1 · Structure
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DAC 5945
Muscarinic Antagonist
DAC 5945 is a potent muscarinic antagonist primarily targeting M1 and M2 receptors, exhibiting pKi values of 8.3 and 7.52, respectively. Its selectivity for the airways over cardiac tissue makes it a valuable compound for research related to respiratory disorders. DAC 5945 can be employed in investigations of airway smooth muscle modulation and in studies aimed at understanding the role of muscarinic receptors in various physiological and pathological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 124065-13-0 |
| Applications | Muscarinic Antagonist |
| Formula | C19H30ClN3O |
| Molecular Weight | 351.91 |
| SMILES | OC(C1=CC=CC=C1)(C2CCCCC2)CN3CCN(C=N)CC3.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.