Dapagliflozin-d4

Catalog No.: A68417
Stable Isotope
Dapagliflozin-d4 is a stable isotope-labeled form of Dapagliflozin, an SGLT2 inhibitor that effectively targets sodium/glucose cotransport in the treatment of diabetes mellitus (DM). This compound promotes glucose excretion via urine, contributing to improved glycemic control. Additionally, Dapagliflozin has been shown to induce HIF1 expression and mitigate renal ischemia-reperfusion injury, making it a valuable tool for research in diabetic complications and renal protection mechanisms.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDapagliflozin-d4 is a stable isotope-labeled form of Dapagliflozin, an SGLT2 inhibitor that effectively targets sodium/glucose cotransport in the treatment of diabetes mellitus (DM). This compound promotes glucose excretion via urine, contributing to improved glycemic control. Additionally, Dapagliflozin has been shown to induce HIF1 expression and mitigate renal ischemia-reperfusion injury, making it a valuable tool for research in diabetic complications and renal protection mechanisms.
Product Information
Catalog NumA68417
FormulaC21H21D4ClO6
Molecular Weight412.90
CAS Number1224234-25-6
SMILESO[C@H]1[C@H](C2=CC(CC3=C([2H])C([2H])=C(C([2H])=C3[2H])OCC)=C(C=C2)Cl)O[C@@H]([C@H]([C@@H]1O)O)CO
SynonymsBMS-512148-d4
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