Fig. 1 · Structure
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Dasatinib intermediate-1
Dasatinib Intermediate
Dasatinib intermediate-1 is a crucial intermediate in the synthesis of Dasatinib, a highly potent ATP-competitive inhibitor of Src and Bcr-Abl kinases. This compound exhibits significant antitumor activity, making it valuable for cancer research and therapeutic development. Its role in the production of Dasatinib facilitates studies focused on targeted therapies for various malignancies, particularly chronic myeloid leukemia.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 302964-08-5 |
| Applications | Dasatinib Intermediate |
| Formula | C16H13Cl2N5OS |
| Molecular Weight | 394.28 |
| SMILES | O=C(C1=CN=C(NC2=NC(C)=NC(Cl)=C2)S1)NC3=C(C)C=CC=C3Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.