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Dazodeunetant

NK Inhibitor

Dazodeunetant is a selective inhibitor of neurokinin receptors (NK), exhibiting an IC50 of 75.99 nM against NK3R in HEK293-NK3 cells. This nitrogen-containing fused ring derivative demonstrates potential in the study of menopausal hot flashes and related therapeutic strategies. Its ability to modulate neurokinin signaling positions it as a valuable tool in neurobiology and women's health research.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2759134-55-7
Applications	NK Inhibitor
Formula	C₁₅H₁₁DClFN₆OS
Molecular Weight	379.82
SMILES	C[C@@H]1C2=NN=C(C3=NC(Cl)=NS3)N2CCN1C(C4=CC([2H])=C(C=C4)F)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.