Biological Activity
DBPR108 is a potent, selective, and orally bioavailable dipeptide-derived inhibitor of DPP4 with IC50 of 15 nM; no inhibition on DDP8 and DPP9.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 30.83 mL | 154.14 mL | 308.27 mL |
0.5 mM | 6.17 mL | 30.83 mL | 61.65 mL |
1 mM | 3.08 mL | 15.41 mL | 30.83 mL |
5 mM | 0.62 mL | 3.08 mL | 6.17 mL |
*The above data is based on the productmolecular weight 324.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A21833 |
---|---|
Actions | Inhibitor |
M. Wt | 324.39 |
Formula | C16H25FN4O2 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1186426-66-3 |
Synonyms | DBPR 108, DBPR 108 |
SMILES | N#C[[email protected]]1N(C(CNC(C)(C)CC(N2CCCC2)=O)=O)C[[email protected]@H](F)C1 |
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