DC07090 dihydrochloride is a potent, reversible, and competitive inhibitor of the human enterovirus 71 (EV71) 3C protease. It exhibits low toxicity with an IC50 of 21.72 μM and a Ki value of 23.29 μM. Additionally, DC07090 dihydrochloride effectively inhibits coxsackievirus A16 (CVA16) replication, with an EC50 of 27.76 μM. This compound is valuable for research into enteroviral infections and potential therapeutic interventions against these viruses.
DC07090 dihydrochloride is a potent, reversible, and competitive inhibitor of the human enterovirus 71 (EV71) 3C protease. It exhibits low toxicity with an IC50 of 21.72 μM and a Ki value of 23.29 μM. Additionally, DC07090 dihydrochloride effectively inhibits coxsackievirus A16 (CVA16) replication, with an EC50 of 27.76 μM. This compound is valuable for research into enteroviral infections and potential therapeutic interventions against these viruses.
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