DC661

Catalog No.: A17236

PPT1 inhibitor

DC661

DC661 Chemical Structure

CAS NO. 1872387-43-3

DC661 is a potent palmitoyl-protein thioesterase 1 (PPT1) inhibitor. DC661 inhibits autophagy. DC661 is capable of deacidifying the lysosome and inhibiting autophagy significantly better than hydroxychloroquine (HCQ).

Availability: In stock

Package Price Qty
2 mg

Regular Price: $100.00

Special Price $80.00

5 mg

Regular Price: $200.00

Special Price $160.00

10 mg

Regular Price: $320.00

Special Price $256.00

50 mg

Regular Price: $1,100.00

Special Price $880.00

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Biological Activity

DC661 is a potent palmitoyl-protein thioesterase 1 (PPT1) inhibitor. DC661 inhibits autophagy. DC661 is capable of deacidifying the lysosome and inhibiting autophagy significantly better than hydroxychloroquine (HCQ).
In vitro DMSO 55 mg/mL (99.53 mM)
Water Insoluble
Ethanol 44 mg/mL (79.62 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.1 mL 90.48 mL 180.97 mL
0.5 mM 3.62 mL 18.1 mL 36.19 mL
1 mM 1.81 mL 9.05 mL 18.1 mL
5 mM 0.36 mL 1.81 mL 3.62 mL

*The above data is based on the productmolecular weight 552.588. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17236
Actions Inhibitor
CAS No. 1872387-43-3
Formula C31H39Cl2N5
M. Wt 552.588
Purity >98%
Synonyms DC-661; DC 661;
SMILES CN(CCCCCCNC1=CC=NC2=CC(Cl)=CC=C12)CCCCCCNC3=CC=NC4=CC(Cl)=CC=C34
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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