Fig. 1 · Structure

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DCN1-UBC12-IN-2

DCN1-UBC12 Inhibitor

DCN1-UBC12-IN-2 is a potent inhibitor of the DCN1-UBC12 interaction, with an IC50 of 9.55 nM. This compound specifically targets the DCN1-UBC12 pathway, demonstrating efficacy in mitigating Ang II-induced activation of cardiac fibroblasts. It serves as a valuable tool for research into cardiac fibrosis and related signaling pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2374827-47-9
Applications DCN1-UBC12 Inhibitor
Formula C23H20ClN7O3S2
Molecular Weight 542.03
SMILES
N#CC1=C(C2=CC(OC)=C(OC)C(OC)=C2)N=C(SCC3=CC=C(Cl)C=C3)N=C1SC4=NN=NN4C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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