DCSM06-05 is a potent inhibitor of the SMARCA2-BRD interaction, exhibiting an IC50 value of 9 µM and a Kd value of 22.4 µM. This compound is instrumental in studies focused on chromatin remodeling and precision oncology, as it modulates the activity of the SWI/SNF complex. Research applications include investigating the role of SMARCA2 in tumorigenesis and therapeutic resistance in various cancers.
DCSM06-05 is a potent inhibitor of the SMARCA2-BRD interaction, exhibiting an IC50 value of 9 µM and a Kd value of 22.4 µM. This compound is instrumental in studies focused on chromatin remodeling and precision oncology, as it modulates the activity of the SWI/SNF complex. Research applications include investigating the role of SMARCA2 in tumorigenesis and therapeutic resistance in various cancers.
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