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DDR1-IN-1 dihydrochloride

Catalog No.: A21813

DDR1 receptor tyrosine kinase inhibitor

DDR1-IN-1 dihydrochloride

DDR1-IN-1 dihydrochloride Chemical Structure

CAS NO. 1780303-76-5

DDR1-IN-1 dihydrochloride is a potent and selective DDR1 receptor tyrosine kinase inhibitor with an IC50 of 105 nM; 4-fold less potent for DDR2 (IC50 = 413 nM).

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

DDR1-IN-1 dihydrochloride is a potent and selective DDR1 receptor tyrosine kinase inhibitor with an IC50 of 105 nM; 4-fold less potent for DDR2 (IC50 = 413 nM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.99 mL 79.93 mL 159.87 mL
0.5 mM 3.2 mL 15.99 mL 31.97 mL
1 mM 1.6 mL 7.99 mL 15.99 mL
5 mM 0.32 mL 1.6 mL 3.2 mL

*The above data is based on the productmolecular weight 625.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21813
Actions Inhibitor
CAS No. 1780303-76-5
Formula C30H33Cl2F3N4O3
M. Wt 625.51
Purity >98%
SMILES CC1=C(C=C(C=C1)NC(C2=CC=C(C(C(F)(F)F)=C2)CN3CCN(CC3)CC)=O)OC4=CC(C5)=C(C=C4)NC5=O.Cl.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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