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Biological Activity
DDR1-IN-1 dihydrochloride is a potent and selective DDR1 receptor tyrosine kinase inhibitor with an IC50 of 105 nM; 4-fold less potent for DDR2 (IC50 = 413 nM).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 15.99 mL | 79.93 mL | 159.87 mL |
| 0.5 mM | 3.2 mL | 15.99 mL | 31.97 mL |
| 1 mM | 1.6 mL | 7.99 mL | 15.99 mL |
| 5 mM | 0.32 mL | 1.6 mL | 3.2 mL |
*The above data is based on the productmolecular weight 625.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21813 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1780303-76-5 |
| Formula | C30H33Cl2F3N4O3 |
| M. Wt | 625.51 |
| Purity | >98% |
| SMILES | CC1=C(C=C(C=C1)NC(C2=CC=C(C(C(F)(F)F)=C2)CN3CCN(CC3)CC)=O)OC4=CC(C5)=C(C=C4)NC5=O.Cl.Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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