DDR1-IN-1

Catalog No.: A13985

DDR1 receptor inhibitor

DDR1-IN-1

DDR1-IN-1 Chemical Structure

CAS NO. 1449685-96-4

DDR1-IN-1 is a potent and selective DDR1 receptor tyrosine kinase inhibitor with IC50/EC50 of 105 nM/87 nM, 4-fold less potent for DDR2 (IC50= 413 nM).

Availability: In stock

Package Price Qty
5 mg
$80.00
10 mg
$125.00
25 mg
$250.00
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Biological Activity

DDR1-IN-1 is a potent and selective DDR1 receptor tyrosine kinase inhibitor with IC50/EC50 of 105 nM/87 nM, 4-fold less potent for DDR2 (IC50= 413 nM).
Targets
DDR1 DDR2
105 nM413 nM
In vitro DMSO Warmed: 87 mg/mL (157.44 mM)
Water Insoluble
Ethanol Warmed: 3 mg/mL (5.42 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.1 mL 90.48 mL 180.97 mL
0.5 mM 3.62 mL 18.1 mL 36.19 mL
1 mM 1.81 mL 9.05 mL 18.1 mL
5 mM 0.36 mL 1.81 mL 3.62 mL

*The above data is based on the productmolecular weight 552.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13985
Actions Inhibitor
CAS No. 1449685-96-4
Formula C30H31F3N4O3
M. Wt 552.59
Purity >98%
SMILES CCN1CCN(CC1)CC2=C(C=C(C=C2)C(=O)NC3=CC(=C(C=C3)C)OC4=CC5=C(C=C4)NC(=O)C5)C(F)(F)F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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