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DDR1-IN-1 is a potent and selective DDR1 receptor tyrosine kinase inhibitor with IC50/EC50 of 105 nM/87 nM, 4-fold less potent for DDR2 (IC50= 413 nM).
Targets
| DDR1 | DDR2 | |||
| 105 nM | 413 nM |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.1 mL | 90.48 mL | 180.97 mL |
| 0.5 mM | 3.62 mL | 18.1 mL | 36.19 mL |
| 1 mM | 1.81 mL | 9.05 mL | 18.1 mL |
| 5 mM | 0.36 mL | 1.81 mL | 3.62 mL |
*The above data is based on the productmolecular weight 552.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13985 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 552.59 |
| Formula | C30H31F3N4O3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1449685-96-4 |
| SMILES | CCN1CCN(CC1)CC2=C(C=C(C=C2)C(=O)NC3=CC(=C(C=C3)C)OC4=CC5=C(C=C4)NC(=O)C5)C(F)(F)F |
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