Decitabine

Catalog No.: A10292

DNA Methyltransferase Inhibitors

Decitabine

Decitabine Chemical Structure

CAS NO. 2353-33-5

Decitabine is a hypomethylating agent.It hypomethylates DNA by inhibiting DNA methyltransferase.

Availability: In stock

Package Price Qty
10 mg
$40.00
25 mg
$70.00
50 mg
$100.00
100 mg
$130.00
10mM * 1mL in DMSO
$50.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Bracha Shraibman, .et al. Human Leukocyte Antigen (HLA) Peptides Derived from Tumor Antigens Induced by Inhibition of DNA Methylation for Development of Drug-facilitated Immunotherapy, Mol Cell Proteomics, 2016, Sep; 15(9): 3058-3070 PMID: 27412690

Biological Activity

Decitabine is a hypomethylating agent.It hypomethylates DNA by inhibiting DNA methyltransferase.
Targets
DNA methylation (HL-60, KG1a cells)
In vitro (25°C) DMSO 45 mg/mL (197.18 mM)
Water 10 mg/mL (43.81 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 43.82 mL 219.11 mL 438.21 mL
0.5 mM 8.76 mL 43.82 mL 87.64 mL
1 mM 4.38 mL 21.91 mL 43.82 mL
5 mM 0.88 mL 4.38 mL 8.76 mL

*The above data is based on the productmolecular weight 228.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10292
Actions Inhibitor
M. Wt 228.2
Formula C8H12N4O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2353-33-5
Synonyms Dacogen
SMILES C1[[email protected]@H]([[email protected]](O[[email protected]]1N2C=NC(=NC2=O)N)CO)O

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