Decitabine

Catalog No.: A10292
DNA Methyltransferase Inhibitors
Decitabine is a hypomethylating agent.It hypomethylates DNA by inhibiting DNA methyltransferase.
Grouped product items
Product Name Price Stock Qty
Decitabine 10mg
$40.00
In stock
Decitabine 25mg
$70.00
In stock
Decitabine 50mg
$100.00
In stock
Decitabine 100mg
$130.00
In stock
Decitabine 10mM * 1mL in DMSO
$50.00
In stock
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Adooq Products cited in reputable paper
Adooq's Decitabine has been cited by 5 publications
  • Tianxing Ying, .et al. , Cancers (Basel), 2022, Dec 30;15(1):243 PMID: 36612238
  • Borbala Szabo, .et al. , J Clin Endocrinol Metab, 2022, Sep 5;dgac496 PMID: 36059148
  • Sangni Qian, .et al. , Clin Epigenetics, 2022, Sep 5;14(1):111 PMID: 36064442
  • Borbála Szabó, .et al. , J Clin Endocrinol Metab, 2020, Jun 1;105(6):dgaa156 PMID: 32232382
  • Bracha Shraibman, .et al. , Mol Cell Proteomics, 2016, Sep; 15(9): 3058-3070 PMID: 27412690
  • gg
    Biological Activity
    Discription Decitabine is a hypomethylating agent.It hypomethylates DNA by inhibiting DNA methyltransferase.
    Targets
    Target Value
    Product Information
    Catalog Num A10292
    Formula C8H12N4O4
    Molecular Weight 228.2
    CAS Number 2353-33-5
    SMILES C1[C@@H]([C@H](O[C@H]1N2C=NC(=NC2=O)N)CO)O
    Synonyms Dacogen, 5-Aza-dC
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 44 mg/mL (192.8 mM)
    Water 10 mg/mL (43.81 mM)
    Ethanol Insoluble
    In vivo water 9 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 43.82 mL 219.11 mL 438.21 mL
    0.5 mM 8.76 mL 43.82 mL 87.64 mL
    1 mM 4.38 mL 21.91 mL 43.82 mL
    5 mM 0.88 mL 4.38 mL 8.76 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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