Fig. 1 · Structure
Documents & Downloads
Deg-1
DNA Probe
Deg-1 is a bifunctional DNA probe that features both a cleavage group and a covalent binding moiety. It covalently attaches to target nucleic acids and acts as a click-degrader, enabling the selective cleavage of nucleic acid molecules within cells. Deg-1 contains an azide functional group, allowing it to engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds, as well as ring strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-linked molecules. This compound is valuable for applications in nucleic acid research and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2761446-55-1 |
| Applications | DNA Probe |
| Formula | C15H27N5O5 |
| Molecular Weight | 357.41 |
| SMILES | [N-]=[N+]=NCCOCCOCCOCCOCCOCCN1C=NC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.