Fig. 1 · Structure
Documents & Downloads
Denagliptin
Cat. No.
A74397
CAS
483369-58-0
Endogenous Metabolite
Denagliptin is a small molecule inhibitor of dipeptidyl peptidase IV (DPP-4), primarily targeting endogenous metabolites involved in glucose metabolism. This compound demonstrates significant activity in the research of type 2 diabetes and offers insights into endocrine and metabolic disorders. While stable in the solid state, Denagliptin is known to degrade in solution and in various excipient mixtures, with degradation primarily occurring through cyclization reactions. Understanding its degradation pathways is crucial for advancing formulation development and regulatory compliance.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 483369-58-0 |
| Applications | Endogenous Metabolite |
| Formula | C20H18F3N3O |
| Molecular Weight | 373.37 |
| Synonyms | GSK823093 |
| SMILES | O=C(N1[C@@H](C[C@@H](C1)F)C#N)[C@@H](N)C(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.