RW3

Catalog No.: A48225
Antimicrobial Peptide
RW3 is a cationic antimicrobial hexapeptide that primarily targets the bacterial cytoplasmic membrane, disrupting cellular respiration and inhibiting cell wall synthesis. It demonstrates potent bioactivity against Gram-positive bacteria, including Bacillus subtilis 168, with a minimum inhibitory concentration (MIC) of 2 µg/mL. Additionally, RW3 induces morphological changes in murine erythrocytes. This reagent is suitable for applications in antimicrobial and antifungal research.
Grouped product items
Size Price Stock Qty
5mg
$50.00
In stock
10mg
$80.00
In stock
25mg
$145.00
In stock
50mg
$215.00
In stock
100mg
$315.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionRW3 is a cationic antimicrobial hexapeptide that primarily targets the bacterial cytoplasmic membrane, disrupting cellular respiration and inhibiting cell wall synthesis. It demonstrates potent bioactivity against Gram-positive bacteria, including Bacillus subtilis 168, with a minimum inhibitory concentration (MIC) of 2 µg/mL. Additionally, RW3 induces morphological changes in murine erythrocytes. This reagent is suitable for applications in antimicrobial and antifungal research.
Product Information
Catalog NumA48225
FormulaC51H69N19O6
Molecular Weight1044.22
CAS Number359632-11-4
SequenceArg-Trp-Arg-Trp-Arg-Trp-NH2
Sequence shorteningRWRWRW-NH2
SMILESC([C@H](NC([C@@H](NC([C@H](CC=1C=2C(NC1)=CC=CC2)NC([C@H](CCCNC(=N)N)N)=O)=O)CCCNC(=N)N)=O)C(N[C@H](C(N[C@@H](CC=3C=4C(NC3)=CC=CC4)C(N)=O)=O)CCCNC(=N)N)=O)C=5C=6C(NC5)=CC=CC6
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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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