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Des-Arg10-HOE I40

Bradykinin B1 Receptor Antagonist

[Des-Arg10]-HOE I40 is a potent antagonist of the bradykinin B1 receptor, known for its ability to inhibit bradykinin-induced signaling. This compound plays a significant role in research investigating inflammatory processes and pain pathways, particularly in conditions associated with bradykinin receptor activation. Its effectiveness in blocking B1 receptor activity makes it a valuable tool for studying the therapeutic potential in various pathological states.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	1054763-33-5
Applications	Bradykinin B1 Receptor Antagonist
Formula	C₅₃H₇₇N₁₅O₁₂S
Molecular Weight	1148.34
SMILES	C(=O)([C@H]1C=2C(CCN1C([C@@H](NC([C@H](CC3=CC=CS3)NC(CNC(=O)[C@H]4N(C(=O)[C@H]5N(C([C@@H](NC([C@@H](CCCNC(=N)N)N)=O)CCCNC(=N)N)=O)CCC5)C[C@H](O)C4)=O)=O)CO)=O)=CC=CC2)N6[C@@]7([C@](C[C@H]6C(O)=O)(CCCC7)[H])[H]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.