Fig. 1 · Structure
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Desethyl chloroquine
Antiplasmodic Agent
Desethyl chloroquine is a significant desethyl metabolite of chloroquine, functioning primarily as an antiplasmodic agent. This compound exhibits inhibitory effects on autophagy and toll-like receptors (TLRs), contributing to its biological activity. Desethyl chloroquine is utilized in research focusing on malaria treatment mechanisms and the modulation of immune responses.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1476-52-4 |
| Applications | Antiplasmodic Agent |
| Formula | C16H22ClN3 |
| Molecular Weight | 291.82 |
| SMILES | CC(NC1=CC=NC2=CC(Cl)=CC=C12)CCCNCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.