Fig. 1 · Structure
Documents & Downloads
Desipramine
Norepinephrine Reuptake Inhibitor
Desipramine is a tricyclic antidepressant that functions primarily as a norepinephrine reuptake inhibitor. It exhibits significant antidepressant activity by enhancing norepinephrine levels in the central nervous system. This compound is also utilized in studies investigating the modulation of pharyngeal collapsibility through its effects on sleep-related genioglossus activity, making it relevant for research into sleep apnea and related respiratory disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 50-47-5 |
| Applications | Norepinephrine Reuptake Inhibitor |
| Formula | C18H22N2 |
| Molecular Weight | 266.38 |
| SMILES | CNCCCN1C2=CC=CC=C2CCC3=CC=CC=C31 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.