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DF 461

Name: DF 461
Brand: Adooq Bioscience
SKU: A73455
Availability: OutOfStock

Cat. No. A73455 CAS 937051-40-6

Endogenous Metabolite

DF 461 is a selective sterol synthase inhibitor that effectively impairs cholesterol biosynthesis. Demonstrating high specificity for liver tissue, DF 461 significantly reduces cholesterol synthesis in rat liver models. This compound has also been shown to lower plasma lipid levels in repeated dosing studies in non-rodent species, making it valuable for research applications related to lipid metabolism and cardiovascular health.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	937051-40-6
Applications	Endogenous Metabolite
Formula	C₂₀H₁₄Cl₂F₃N₃O₄
Molecular Weight	488.24
SMILES	O=C(O)C[C@@H]1C2=NN=C(C(F)(F)F)N2C3=CC=C(Cl)C=C3[C@@H](C4=CC=CC(OC)=C4Cl)O1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.