Di(4-morpholine-amide)-4-DTM-phenoxy(3,5-F)-O-PEG3-CH2COOH

Catalog No.: A43210
ADC Linker
Di(4-morpholine-amide)-4-DTM-phenoxy(3,5-F)-O-PEG3-CH2COOH functions as a cleavable PEG-based linker for antibody-drug conjugates (ADCs). This compound facilitates the attachment of cytotoxic agents to antibodies while maintaining stability in circulation and enabling targeted delivery. Its strategic design enhances drug release in the targeted cellular environment, making it invaluable for research in cancer therapeutics and ADC development.
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Size Stock
5mg
10mg
50mg
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Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionDi(4-morpholine-amide)-4-DTM-phenoxy(3,5-F)-O-PEG3-CH2COOH functions as a cleavable PEG-based linker for antibody-drug conjugates (ADCs). This compound facilitates the attachment of cytotoxic agents to antibodies while maintaining stability in circulation and enabling targeted delivery. Its strategic design enhances drug release in the targeted cellular environment, making it invaluable for research in cancer therapeutics and ADC development.
Product Information
Catalog NumA43210
FormulaC40H41F2N3O12S2
Molecular Weight857.89
CAS Number2227349-05-3
SMILESO=C(COCCOCCOCCOC1=C(C=C(N2C(C(SC3=CC=C(C(N4CCOCC4)=O)C=C3)=C(C2=O)SC5=CC=C(C(N6CCOCC6)=O)C=C5)=O)C=C1F)F)O
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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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