Fig. 1 · Structure
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Di-O-methyldemethoxycurcumin
IL-6 Inhibitor
Di-O-methyldemethoxycurcumin is a curcuminoid analog that primarily targets IL-6, exhibiting potent inhibitory activity with an EC50 of 16.20 μg/mL. This compound demonstrates significant anti-inflammatory and antioxidant properties, making it valuable for research in inflammation-related pathways and oxidative stress studies. Its functional role in modulating cytokine production positions it as a useful tool for investigating therapeutic strategies in various inflammatory diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 824951-60-2 |
| Applications | IL-6 Inhibitor |
| Formula | C22H22O5 |
| Molecular Weight | 366.41 |
| SMILES | O=C(CC(/C=C/C1=CC=C(OC)C=C1)=O)/C=C/C2=CC=C(OC)C(OC)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.